Search on: BCL2 FAMILY PROTEINS 
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Descriptor English:   Proto-Oncogene Proteins c-bcl-2 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-bcl-2 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-bcl-2 
Synonyms English:   B-Cell Leukemia 2 Family Proteins
BCL2 Family Proteins
BCL2 Proteins
B Cell Leukemia 2 Family Proteins
Family Proteins, BCL2
Proteins, BCL2
Proteins, BCL2 Family
Proto Oncogene Proteins c bcl 2
Proto-Oncogene Proteins, bcl-2
bcl 2 Proto Oncogene Proteins
c bcl 2 Proteins
c-bcl-2, Proto-Oncogene Proteins
bcl-2 Proto-Oncogene Proteins
c-bcl-2 Proteins  
Tree Number:   D12.644.360.075.718
D12.776.476.075.718
D12.776.624.664.700.169
Definition English:   Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma. 
History Note English:   97; was PROTO-ONCOGENE PROTEIN BCL-2 (NM) 1989-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33061 
Unique Identifier:   D019253 

Occurrence in VHL:
 

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